| Factor Information | |
|---|---|
| Data ID | 507 |
| Factor | 6 year full-scale IQ |
| Description | Two-year cognitive score and 6-year Full-scale IQ were poorer in children with neonatal white matter injury. |
| Biomarker | NA |
| Classification | F5 (psychosocial factor - intelligence) |
| Association | |
|---|---|
| Application | prognosis |
| Objective | 6-year Full-scale IQ were poorer |
| p Value | <0.05 |
| Conclusion | provide evidence of unfavourable outcome in school-age children with critical CHD who acquire perioperative neonatal brain injury. |
| Risk Factor | protective factor |
| CHD Type | |
|---|---|
| ID | 463 |
| CHD Type | isolated CHD/non-isolated CHD |
| CHD Subtype | SV/HLHS/Taussig–Bing anomaly/IAA, HAA/CoA, HAA |
| Reference | |
|---|---|
| PMID | 29572821 |
| Year | 2018 |
| Title | Perioperative neonatal brain injury is associated with worse school-age neurodevelopment in children with critical congenital heart disease. |
| Sample | ||
|---|---|---|
| Population | children | |
| Source | Brain | |
| Region | Utrecht, Netherlands | |
| Method | cerebral magnetic resonance imaging; neurodevelopment was assessed at 24 months & 6 years, Brain injury, brain volumes, and cortical measures | |
| Race | Europe | |
| Disease History | N/A | |
| Treatment History | neonatal cardiac surgery | |
| Group | WMI moderate–severe(Treatment) | WMI no–mild(Control) |
| Number | 19 | 13 |
| Age | Median (IQR) gestational age: 39.1 (38.7–40.0) wks | Median (IQR) gestational age: 39.1 (38.7–40.0) wks |
| Gender (Male: Female) | N/A | N/A |
| Marker Level | 85 (78-103) | 101 (91-113 |
