| Factor Information | |
|---|---|
| Data ID | 513 |
| Factor | Median RDW |
| Description | Red cell distribution width (RDW) is a standard component of the automated blood count, and is of prognostic value in heart failure and coronary heart disease. the primary endpoint (death, heart failure, hospitalization, arrhythmia, thromboembolic events, cardiac intervention) occurred in 196 patients (33%). Median RDW was 13.4 (12.8–14.1)% versus 12.9 (12.5– 13.4)% in patients with and without the primary endpoint (P<0.001). RDW was significantly associated with the endpoint when adjusted for age, sex, clinical risk factors, CRP, and NT-proBNP (HR 1.20; 95% CI 1.06–1.35; P=0.003). |
| Biomarker | YES |
| Classification | E11 (physiological factor - physical sign) |
| Association | |
|---|---|
| Application | prognosis and risk assessment |
| Objective | the primary endpoint (death, heart failure, hospitalization, arrhythmia, thromboembolic events, cardiac intervention) |
| p Value | 0.003 |
| HR | 1.2 |
| Conclusion | RDW is associated with cardiovascular events in patients with ACHD, independently of age, sex, clinical risk factors, CRP, and NT-proBNP. This readily available biomarker could therefore be considered as an additive biomarker for risk stratification in these patients. |
| Risk Factor | risk factor (article mentioned) |
| CHD Type | |
|---|---|
| ID | 148 |
| CHD Type | NA |
| CHD Subtype | NA |
| Reference | |
|---|---|
| PMID | 29525069 |
| Year | 2018 |
| Title | Red cell distribution width in adults with congenital heart disease: A worldwide available and low-cost predictor of cardiovascular events. |
| Sample | ||
|---|---|---|
| Population | Adults | |
| Source | venous blood | |
| Region | Rotterdam, Netherlands | |
| Method | prospective cohort study | |
| Race | Europe | |
| Disease History | N/A | |
| Treatment History | N/A | |
| Group | patients with the primary endpoint(Treatment) | patients without the primary endpoint(Control) |
| Number | 196 | 396 |
| Age | median age 33 [IQR 25–41] years | median age 33 [IQR 25–41] years |
| Gender (Male: Female) | N/A | N/A |
| Marker Level | Median RDW:13.4 (12.8–14.1)% | Median RDW:12.9 (12.5–13.4)% |
