| Factor Information | |
|---|---|
| Data ID | 592 |
| Factor | genotype of AhR p.Arg554Lys(Arg/Arg) |
| Description | N/A |
| Biomarker | NA |
| Classification | D1 (molecular factor - DNA) |
| Association | |
|---|---|
| Application | risk assessment and prognosis |
| Objective | children with CHD |
| p Value | 0.001 |
| Conclusion | The genotype of AhR p.Arg554Lys differed significantly between patients and controls. |
| Risk Factor | unknown |
| CHD Type | |
|---|---|
| ID | 471 |
| CHD Type | isolated CHD |
| CHD Subtype | VSD/ASD/TOF/AVSD/DORV/TGA |
| Reference | |
|---|---|
| PMID | 29185192 |
| Year | 2018 |
| Title | A Functional Aryl Hydrocarbon Receptor Genetic Variant, Alone and in Combination with Parental Exposure, is a Risk Factor for Congenital Heart Disease |
| Sample | ||
|---|---|---|
| Population | children | |
| Source | blood | |
| Region | Italy, Pisa | |
| Method | Real time-PCR | |
| Race | European | |
| Disease History | N/A | |
| Treatment History | N/A | |
| Group | CHD patient(Treatment) | control(Control) |
| Number | 68 | 211 |
| Age | 6.2±6.7 years | at birth |
| Gender (Male: Female) | N/A | N/A |
| Marker Level | 0.53 | 0.77 |
