| Factor Information | |
|---|---|
| Data ID | 605 |
| Factor | paternal exposure combined with Arg/Arg |
| Description | N/A |
| Biomarker | NA |
| Classification | Z (combined factor - combined factor) |
| Association | |
|---|---|
| Application | risk assessment and prognosis |
| Objective | Interaction analysis between the AhR polymorphism and paternal exposures)children with CHD |
| p Value | 0.01 |
| OR | 2 |
| Conclusion | There was significant elevated CHD risk with paternal exposure. |
| Risk Factor | risk factor |
| CHD Type | |
|---|---|
| ID | 471 |
| CHD Type | isolated CHD |
| CHD Subtype | VSD/ASD/TOF/AVSD/DORV/TGA |
| Reference | |
|---|---|
| PMID | 29185192 |
| Year | 2018 |
| Title | A Functional Aryl Hydrocarbon Receptor Genetic Variant, Alone and in Combination with Parental Exposure, is a Risk Factor for Congenital Heart Disease |
| Sample | ||
|---|---|---|
| Population | children | |
| Source | questionnaires | |
| Region | Italy, Pisa | |
| Method | T-test and unconditional logistic regression analysis;Real time-PCR | |
| Race | European | |
| Disease History | N/A | |
| Treatment History | N/A | |
| Group | CHD patient(Treatment) | control(Control) |
| Number | 37 | 67 |
| Age | N/A | N/A |
| Gender (Male: Female) | N/A | N/A |
| Marker Level | 37(29%) | 67(13.1%) |
