| Factor Information | |
|---|---|
| Data ID | 735 |
| Factor | mean global brain volumes , TBV(all pre and post-operative data) |
| Description | N/A |
| Biomarker | NA |
| Classification | A3 (clinical factor - disease & symptom) |
| Association | |
|---|---|
| Application | prognosis |
| Objective | Compare the mean global and regional brain volumes between CHD with and without brain injury. |
| p Value | <0.0001 |
| Conclusion | Mean global and regional brain volumes (all pre- and post-operative data points combined) were higher in subjects without brain injury as compared to those with brain injury. |
| Risk Factor | unknown |
| CHD Type | |
|---|---|
| ID | 479 |
| CHD Type | isolated CHD/non-isolated CHD |
| CHD Subtype | HLHS/TGA/TGA, VSD |
| Reference | |
|---|---|
| PMID | 28918207 |
| Year | 2018 |
| Title | The association between cardiac physiology, acquired brain injury and postnatal brain growth in critical congenital heart disease |
| Sample | ||
|---|---|---|
| Population | neonate | |
| Source | data | |
| Region | USA,California | |
| Method | T-test | |
| Race | American | |
| Disease History | N/A | |
| Treatment History | cardiac operation | |
| Group | with brain injury(Treatment) | without brain injury(Control) |
| Number | pre and post-operative injury: 17 and 14 of TGA; 13 and 15 of HLHS | pre and post- operative injury: 32 and 32 of TGA; 17 and 12 of HLHS |
| Age | N/A | N/A |
| Gender (Male: Female) | N/A | N/A |
| Marker Level | TBV:359cm3 | TBV:385cm3 |
