| Factor Information | |
|---|---|
| Data ID | 771 |
| Factor | growth differentiation factor-15(GDF-15) |
| Description | N/A |
| Biomarker | YES |
| Classification | E2 (physiological factor - biochemical index) |
| Association | |
|---|---|
| Application | prognosis |
| Objective | children with CHD |
| p Value | <0.01 |
| Conclusion | Plasma GDF-15 levels were significantly higher in PAH-CHD group than in the health control group and CHD group. |
| Risk Factor | unknown |
| CHD Type | |
|---|---|
| ID | 482 |
| CHD Type | isolated CHD/non-isolated CHD |
| CHD Subtype | CHD with LTRS/PDA/ASD/VSD, PDA/VSD/DORV/AVSD |
| Reference | |
|---|---|
| PMID | 28819713 |
| Year | 2017 |
| Title | Plasma Growth Differentiation Factor-15 is a Potential Biomarker for Pediatric Pulmonary Arterial Hypertension Associated with Congenital Heart Disease |
| Sample | ||
|---|---|---|
| Population | children | |
| Source | data | |
| Region | China,Sichuan | |
| Method | T-test | |
| Race | Asian | |
| Disease History | N/A | |
| Treatment History | N/A | |
| Group | PAH-CHD(Treatment) | health control group & CHD without PAH(Control) |
| Number | 46 | 39(CHD without PAH), 30(health control group) |
| Age | 57±27.9 months | 53±33.7 months(CHD without PAH), 56±24.2 months(health control group) |
| Gender (Male: Female) | 18:28 (PAH-CHD) | 14:25 (CHD without PAH), '10:20 (health control group) |
| Marker Level | 1415 ng/L | 611.9ng/L(health control group); 890.6ng/L(CHD without PAH) |
