| Factor Information | |
|---|---|
| Data ID | 844 |
| Factor | Cardiac complications(n=463)--maternal age |
| Description | There is an increasing prevalence of women with congenital heart defects reaching childbearing age. In western countries women tend to give birth at a higher age compared to some decades ago. |
| Biomarker | NA |
| Classification | A3 (clinical factor - disease & symptom) |
| Association | |
|---|---|
| Application | risk assessment |
| Objective | We evaluated the CARdiac disease in PREGnancy (CARPREG) and modified World Health Organization (mWHO) risk classifications for cardiac complications during pregnancies in women with congenital heart defects and analyzed the impact of age on risk of obstetric and fetal outcome. |
| p Value | 0.054 |
| Conclusion | Pregnancy complications in women with congenital heart disease are common but severe complications are rare. Advanced maternal age does not seem to affect complication rate. Existing risk classification systems are insufficient in predicting complications |
| Risk Factor | unrelated |
| CHD Type | |
|---|---|
| ID | 485 |
| CHD Type | isolated CHD/non-isolated CHD |
| CHD Subtype | VSD/VSD, PDA/RV/ASD/PAPVR/AVSD/HCM/AS/AR/MS/TOF/MR/PA/IVS/ccTGA/other |
| Reference | |
|---|---|
| PMID | 28539207 |
| Year | 2017 |
| Title | Effect of maternal age and cardiac disease severity on outcome of pregnancy in women with congenital heart disease. |
| Sample | ||
|---|---|---|
| Population | pregnant women | |
| Source | A single-center observational study | |
| Region | Gothenburg, Sweden | |
| Method | The women were categorized retrospectively according to CARPREG risk score and mWHO class by the authors. | |
| Race | Europe | |
| Disease History | N/A | |
| Treatment History | N/A | |
| Group | maternal age ≤ 35 years(Treatment) | maternal age > 35 years(Control) |
| Number | 50 (total: 496 pregnancies in 232 women) | 15 (total: 496 pregnancies in 232 women) |
| Age | ≤ 35 years | > 35 years |
| Gender (Male: Female) | 0:50 | 0:15 |
| Marker Level | 0.13 | 0.21 |
