| Factor Information | |
|---|---|
| Data ID | 878 |
| Factor | before corrective surgery--CD62P (soluble platelet selectin) (ng/ml) |
| Description | Serum levels of several biomarkers in children with congenital heart disease and healthy agematchedcontrols before corrective surgery. |
| Biomarker | YES |
| Classification | E2 (physiological factor - biochemical index) |
| Association | |
|---|---|
| Application | prognosis |
| Objective | To investigate the influence of surgical correction on biomarkers of endothelial dysfunction in children with congenital heart disease and to evaluate anthropometric data. |
| p Value | <0.01 |
| Conclusion | Among the various blood biomarkers, only CD62P and IGF-1 levels showed statistically significant differences from the control group before corrective surgery. |
| Risk Factor | unknown |
| CHD Type | |
|---|---|
| ID | 490 |
| CHD Type | isolated CHD/non-isolated CHD |
| CHD Subtype | TOF/PAH/VSD/ASD/VSD, ASD/PDA/VSD, ASD, PDA/VSD, CoA/ECD |
| Reference | |
|---|---|
| PMID | 28415932 |
| Year | 2017 |
| Title | The effects of corrective surgery on endothelial biomarkers and anthropometric data in children with congenital heart disease. |
| Sample | ||
|---|---|---|
| Population | children | |
| Source | blood | |
| Region | Taiwan, China | |
| Method | prospective, case-controlled study | |
| Race | Asian | |
| Disease History | N/A | |
| Treatment History | corrective surgery | |
| Group | TOF(Treatment) | control(Control) |
| Number | 15 | 16 |
| Age | 11.7 ± 3.2 months | 12.4 ± 7.7 months |
| Gender (Male: Female) | 9:6 | 12:4 |
| Marker Level | 40.1 (35.4–44.7) | 54.0 (45.4–62.5) |
