| Factor Information | |
|---|---|
| Data ID | 887 |
| Factor | 24–48 hours after corrective surgery--IGF-1 (insulin-like growth factor-1) (ng/ml) |
| Description | Serum levels of several biomarkers in children with congenital heart disease and healthy age-matched controls 24–48 hours after corrective surgery. |
| Biomarker | YES |
| Classification | E2 (physiological factor - biochemical index) |
| Association | |
|---|---|
| Application | prognosis |
| Objective | To investigate the influence of surgical correction on biomarkers of endothelial dysfunction in children with congenital heart disease and to evaluate anthropometric data. |
| p Value | <0.05 |
| Conclusion | Following corrective surgery, CD62E and CD62L decreased rapidly in the PH and TOF groups by comparison with control values, only the reduction of CD62E in the TOF group was nonsignificant. |
| Risk Factor | unknown |
| CHD Type | |
|---|---|
| ID | 490 |
| CHD Type | isolated CHD/non-isolated CHD |
| CHD Subtype | TOF/PAH/VSD/ASD/VSD, ASD/PDA/VSD, ASD, PDA/VSD, CoA/ECD |
| Reference | |
|---|---|
| PMID | 28415932 |
| Year | 2017 |
| Title | The effects of corrective surgery on endothelial biomarkers and anthropometric data in children with congenital heart disease. |
| Sample | ||
|---|---|---|
| Population | children | |
| Source | blood | |
| Region | Taiwan, China | |
| Method | prospective, case-controlled study | |
| Race | Asian | |
| Disease History | N/A | |
| Treatment History | corrective surgery | |
| Group | TOF(Treatment) | control(Control) |
| Number | 15 | 16 |
| Age | 11.7 ± 3.2 months | 12.4 ± 7.7 months |
| Gender (Male: Female) | 9:6 | 12:4 |
| Marker Level | 42.6 (21.5–63.6) (ng/ml) | 92.7 (61.6–123.7)(ng/ml) |
