| Factor Information | |
|---|---|
| Data ID | 889 |
| Factor | Weight--Statistical significance pre- vs post surgery |
| Description | Z-scores for weight and length before and after corrective surgery. |
| Biomarker | NA |
| Classification | E10 (physiological factor - other) |
| Association | |
|---|---|
| Application | prognosis |
| Objective | To evaluate changes in IGF-1 expression with growth, Z scores from height and weight data were assessed pre- and 3–6 months post-surgery. |
| p Value | <0.0001 |
| Conclusion | No significant endothelial dysfunction was observed in children with PH or TOF before or after corrective surgery. Significant retardation of growth, particularly weight, was found before surgery and may be related to IGF-1 suppression. |
| Risk Factor | unknown |
| CHD Type | |
|---|---|
| ID | 490 |
| CHD Type | isolated CHD/non-isolated CHD |
| CHD Subtype | TOF/PAH/VSD/ASD/VSD, ASD/PDA/VSD, ASD, PDA/VSD, CoA/ECD |
| Reference | |
|---|---|
| PMID | 28415932 |
| Year | 2017 |
| Title | The effects of corrective surgery on endothelial biomarkers and anthropometric data in children with congenital heart disease. |
| Sample | ||
|---|---|---|
| Population | children | |
| Source | blood | |
| Region | Taiwan, China | |
| Method | prospective, case-controlled study | |
| Race | Asian | |
| Disease History | N/A | |
| Treatment History | corrective surgery | |
| Group | PH pre-surgery(Treatment) | PH -post corrective surgery(Control) |
| Number | 32 | 32 |
| Age | 9.9 ± 12.3 months | 9.9 ± 12.3 months |
| Gender (Male: Female) | 20:12 | 20:12 |
| Marker Level | –1.83 ± 0.85( –3.50– 0.88) | –0.83 ± 1.00( –2.20–2.20) |
