| Factor Information | |
|---|---|
| Data ID | 939 |
| Factor | folate concentration(ng/ml) |
| Description | FIGN +94762C allele is associated with reduced plasma folate and homocysteine in Han Chinese population |
| Biomarker | NA |
| Classification | E2 (physiological factor - biochemical index) |
| Association | |
|---|---|
| Application | risk assessment |
| Objective | To compare the folate level in different genotypes of FIGN +94762 G>C. |
| p Value | <0.05 |
| Conclusion | FIGN +94762C allele is associated with reduced plasma folate in Han Chinese population. |
| Risk Factor | unknown |
| CHD Type | |
|---|---|
| ID | 492 |
| CHD Type | isolated CHD |
| CHD Subtype | ASD/VSD/TOF/AVSD/TGA/DOLV/DORV |
| Reference | |
|---|---|
| PMID | 28302752 |
| Year | 2017 |
| Title | Lower Circulating Folate Induced by a Fidgetin Intronic Variant Is Associated With Reduced Congenital Heart Disease Susceptibility. |
| Sample | ||
|---|---|---|
| Population | children | |
| Source | Blood and cardiovascular tissue samples | |
| Region | Shanghai,China | |
| Method | Single Nucleotide Polymorphism (SNP) | |
| Race | Asian | |
| Disease History | N/A | |
| Treatment History | N/A | |
| Group | cases(Treatment) | cases(Control) |
| Number | 1036 | 404 |
| Age | 5.24 ± 0.14 years | 5.24 ± 0.14 years |
| Gender (Male: Female) | 819:670 (total) | 819:670 (total) |
| Marker Level | 12.94 ± 0.66 ng/ml(FIGN +94762G>C(Genotype: GG) (rs2119289)--Combined | 11.56 ± 0.80 ng/ml(FIGN +94762G>C(Genotype: GC) (rs2119289)--Combined |
